Reproduction Abstracts

Introduction: Postpartum dairy cows are susceptible to uterine infections that leading to poor fertility. During this period the uterine defence mechanisms were compromised by poor energy status and the preceding viral infections, e.g. bovine herpesvirus 4 (BoHV-4) resulting in uterine pathology initiated by microorganisms. BoHV-4 has been isolated from healthy cows and cows experienced with mastitis, metritis and endometritis worldwide.Methods:...

Introduction: Endometritis is one of the most common reproductive diseases affected postpartum bovine uteri. Lipopolysaccharide (LPS) from Gram-negative bacteria is recognized by Toll-like receptor 4 (TLR4). Binding of LPS and TLR4 mediates the expression of proinflammatory cytokines and chemokines. The excessive inflammatory responses could be involved with endometrial damage.TLR4 antagonist Rhodobacter sphaeroides LPS (RsLPS), is a potent antagonist of LPS from path...